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Re­search Group Meta­bolic In­ter­ac­tions

Group leader

Dr. Manuel Liebeke

MPI for Marine Microbiology
Celsiusstr. 1
D-28359 Bremen
Germany

Room: 

3244

Phone: 

+49 421 2028-8220

Dr. Manuel Liebeke

We use mod­ern mass-spec­tro­metry meth­ods to un­der­stand which mo­lecules are in­volved in mar­ine host-mi­crobe sys­tems, how dif­fer­ent meta­bol­ites shape eco­lo­gical com­munit­ies, and how the sym­bi­otic part­ners re­spond meta­bol­ic­ally to en­vir­on­mental changes.

The re­search in this lab is con­stantly driven by method de­vel­op­ments like high-res­ol­u­tion mass-spec­tro­metry ima­ging to re­veal the spa­tial meta­bolome of mi­cro­bial sys­tems. Our ex­pert­ise is mi­cro­bial meta­bolo­m­ics with a spe­cial fo­cus on mar­ine sys­tems.

Metabolicinteractions
Top Left © Aman Akeerath Mundanatt; Top Right © MARUM; Bottom © HYDRA Institute

Latest News

Showing 1-5 of 19 items.
 

We welcome Bruna Imai to the group

Apr 30, 2023

Hello everyone! My name is Bruna and I will be working on the sea4soCiety project investigating the role of dissolved organic compounds present in coastal ecosystems. More specifically, I will apply Mass spectrometry techniques to identify compounds exuded by Salt Marshes plants and found in pore...

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We welcome our new PhD student, Malin Stüwe

Apr 18, 2023

Hey everyone! My name is Malin. I joined the MS group of the symbiosis department for my PhD. My research will be focused on the characterization of the gut microbiome and metabolic interactions occurring between the host and microbes. The project will be conducted in close collaboration with Kie...

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We welcome our new intern, Adrian Stolfa

Mar 1, 2023

Hello! As a new laboratory assistant at Business Academy Aarhus in Denmark, I am thrilled to be embarking on a journey of discovery and exploration in the field of GC-MS. I am eager to gain hands-on experience in the laboratory and contribute to ongoing research projects. Throughout my internship...

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We welcome our new intern, Tomasz Markowski

Feb 1, 2022

Hi my name is Tomasz and I will be working as laboratory assistant in MS-group in Symbiosis department. An internship in the institute is part of my studies: Chemical and Biotechnical Science at the Business Academy Aarhus. I have always enjoyed working in a field of chemistry and this is the rea...

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Se­lect Pub­lic­a­tions

Michel­lod D, Bien T, Birgel D, Vi­ol­ette M, Kleiner M, Fearn S, Zeidler C, Gruber-Vodicka HR, Du­bilier N, Liebeke M. 2023. De novo phytosterol syn­thesis in an­im­als. Sci­ence
science.org/doi/10.1126/science.add7830
Geier BOetjen JRuth Steiner BPo­likar­pov M, Gruber-Vodicka HR, Liebeke M2021. Con­nect­ing struc­ture and func­tion from or­gan­isms to mo­lecules in small-an­imal sym­bi­oses through chemo-histo-tomo­graphy. PNAS. 118 (27) e2023773118; 10.1073 / pnas.2023773118
Janda M, Seah BKB, Jakob D, Beck­mann J, Geier B, and Liebeke M. 2021. De­term­in­a­tion of Abund­ant Meta­bol­ite Mat­rix Ad­ducts Il­lu­min­ates the Dark Meta­bolome of MALDI-Mass Spec­tro­metry Ima­ging Data­sets. Ana­lyt­ical Chem­istry. 93 (24): 8399-8407. 10.1021 / acs.anal­chem.0c04720 
Geier, B., So­gin, E., Michel­lod, D., Janda, M., Kom­pauer, M., Spen­gler, B., Du­bilier, N. & Liebeke M. 2020. Spa­tial meta­bolo­m­ics of in situ host - mi­crobe in­ter­ac­tions at the mi­cro­meter scale. Nature Mi­cro­bi­o­logy. doi.org/​10.1038/​s41564-019-0664-6
So­gin EM, Puskás E, Du­bilier N, Liebeke M. 2019. Mar­ine Meta­bolo­m­ics: a method for nontar­geted meas­ure­ment of meta­bol­ites in sea­wa­ter by gas chro­ma­to­graphy - mass spec­tro­metry. mSys­tems 4 (6): e00638-19. 10.1128 / mSys­tems.00638-19
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