Group leader
Research Group Metabolic Interactions
MPI for Marine Microbiology
Celsiusstr. 1
D-28359 Bremen
Germany
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Room: |
3244 |
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Phone: |
We use modern mass-spectrometry methods to understand which molecules are involved in marine host-microbe systems, how different metabolites shape ecological communities, and how the symbiotic partners respond metabolically to environmental changes.
The research in this lab is constantly driven by method developments like high-resolution mass-spectrometry imaging to reveal the spatial metabolome of microbial systems. Our expertise is microbial metabolomics with a special focus on marine systems.
We went to the DESY in Hamburg with our host-microbe samples to do super high-resolution scanning. First steps to scan frozen and not-contrasted samples.
Benedikts paper is published - if you like to see more about the connection of high resolution 3D scanning with MALDI-MSI have a look here...
Janine, Dennis and Patric went to the Dreiswerd lab in Münster to look at new spraying methods and look at the newest super high resolution MALDI -imaging source
Benedikt Geier, PhD student in the Department of Symbiosis at the Max Planck Institute for Marine Microbiology, was awarded this year's MSI Award for his innovative method for visualizing and investigating symbioses.
| Michellod D, Bien T, Birgel D, Violette M, Kleiner M, Fearn S, Zeidler C, Gruber-Vodicka HR, Dubilier N, Liebeke M. 2023. De novo phytosterol synthesis in animals. Science science.org/doi/10.1126/science.add7830 |
| Geier B, Oetjen J, Ruth Steiner B, Polikarpov M, Gruber-Vodicka HR, Liebeke M. 2021. Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography. PNAS. 118 (27) e2023773118; 10.1073 / pnas.2023773118 |
| Janda M, Seah BKB, Jakob D, Beckmann J, Geier B, and Liebeke M. 2021. Determination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets. Analytical Chemistry. 93 (24): 8399-8407. 10.1021 / acs.analchem.0c04720 |
| Geier, B., Sogin, E., Michellod, D., Janda, M., Kompauer, M., Spengler, B., Dubilier, N. & Liebeke M. 2020. Spatial metabolomics of in situ host - microbe interactions at the micrometer scale. Nature Microbiology. doi.org/10.1038/s41564-019-0664-6 |
| Sogin EM, Puskás E, Dubilier N, Liebeke M. 2019. Marine Metabolomics: a method for nontargeted measurement of metabolites in seawater by gas chromatography - mass spectrometry. mSystems 4 (6): e00638-19. 10.1128 / mSystems.00638-19 |